EPOP

Across TCGA patient cohorts, EPOP RNA expression is significantly associated with the protein abundance of many other proteins, with 21,380 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible EPOP-associated proteins across cancer lineages are OBI1_S210, WDR75, and XPO5. Each is linked with EPOP in more than 7 cancer types. Because this analysis shows association rather than direction, both EPOP-to-partner and partner-to-EPOP results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, EPOP versus OBI1_S210 in LUAD, with a Pearson correlation of 0.47.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (EPOP→partner) and Y-score (partner→EPOP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	OBI1_S210 →	+1.021	+0.835	<.001	.002	3	8
BRCA	WDR75 →	+0.457	+1.270	<.001	<.001	3	8
LSCC	XPO5 →	+0.651	+1.083	<.001	<.001	3	8
LSCC	RIF1 →	+0.488	+0.966	<.001	<.001	3	7
LUAD	RPL12_S38 →	+1.397	+0.965	<.001	<.001	3	7
BRCA	RRP1B →	+0.543	+1.151	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 21,380 associations by consensus.

EPOP vs OBI1_S210 — LUAD

Explore this scatter interactively →