EPO

Across TCGA patient cohorts, EPO RNA expression is significantly associated with the protein abundance of many other proteins, with 10,021 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible EPO-associated proteins across cancer lineages are ARHGDIB_Y130, PROCR, and CCDC22. Each is linked with EPO in more than 2 cancer types. Because this analysis shows association rather than direction, both EPO-to-partner and partner-to-EPO results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, EPO versus ARHGDIB_Y130 in LSCC, with a Pearson correlation of -0.31.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (EPO→partner) and Y-score (partner→EPO) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	ARHGDIB_Y130 →	-0.483	-0.508	.003	.004	3	3
PDAC	PROCR →	-0.367	-0.269	<.001	<.001	3	3
PDAC	CCDC22 →	-0.177	-0.246	<.001	.002	3	3
GBM	ARPC1B →	-0.350	-0.200	.001	.002	3	3
LSCC	ACTR2 →	-0.221	-0.405	<.001	<.001	3	3
LSCC	ACTR3 →	-0.208	-0.383	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,021 associations by consensus.

EPO vs ARHGDIB_Y130 — LSCC

Explore this scatter interactively →