EPO

Across TCGA patient cohorts, EPO protein abundance is significantly associated with the RNA expression of many other genes, with 7,032 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible EPO-associated genes across cancer lineages are TUT4, PRPF38A, and HS2ST1. Each is linked with EPO in more than 6 cancer types. Because this analysis shows association rather than direction, both EPO-to-partner and partner-to-EPO results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, EPO versus TUT4 in BRCA, with a Pearson correlation of 0.56.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (EPO→partner) and Y-score (partner→EPO) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	TUT4 →	+0.811	+0.463	<.001	<.001	3	7
LSCC	PRPF38A →	+0.480	+0.232	<.001	.001	3	4
HNSC	HS2ST1 →	+0.472	+0.297	.004	.001	3	4
UCEC	SRSF12 →	+0.741	+0.145	<.001	<.001	3	4
LUAD	EIF3I →	+0.326	+0.135	.001	<.001	3	4
HNSC	MYB →	+1.318	+0.324	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,032 associations by consensus.

EPO vs TUT4 — BRCA

Explore this scatter interactively →