EPN3

Across TCGA patient cohorts, EPN3 protein abundance is significantly associated with the RNA expression of many other genes, with 19,564 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible EPN3-associated genes across cancer lineages are LIX1L, FKBP11, and PCDH1. Each is linked with EPN3 in more than 5 cancer types. Because this analysis shows association rather than direction, both EPN3-to-partner and partner-to-EPN3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, EPN3 versus LIX1L in BRCA, with a Pearson correlation of -0.36.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (EPN3→partner) and Y-score (partner→EPN3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	LIX1L →	-0.755	-0.670	<.001	<.001	3	6
OV	FKBP11 →	-0.815	-0.758	<.001	<.001	3	5
HNSC	PCDH1 →	+1.102	+0.619	<.001	<.001	3	5
LSCC	ADAMTS7P4 →	-0.294	-0.569	<.001	<.001	3	5
UCEC	RAB3D →	+0.764	+0.464	.002	.001	3	5
OV	QKI →	-0.560	-0.507	.001	.004	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 19,564 associations by consensus.

EPN3 vs LIX1L — BRCA

Explore this scatter interactively →