EPM2AIP1

Across TCGA patient cohorts, EPM2AIP1 mutation is significantly associated with the RNA expression of many other genes, with 2,714 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible EPM2AIP1-associated genes across cancer lineages are SELENOTP2, MYG1P1, and CYMP. Each is linked with EPM2AIP1 in more than 2 cancer types. Because this analysis shows association rather than direction, both EPM2AIP1-to-partner and partner-to-EPM2AIP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SELENOTP2 grouped by EPM2AIP1-low versus EPM2AIP1-high in LUSC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (EPM2AIP1→partner) and Y-score (partner→EPM2AIP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUSC	SELENOTP2 →	+0.130	+4.561	.006	.005	3	3
HNSC	MYG1P1 →	+0.045	+3.654	<.001	.009	3	2
LIHC	CYMP →	+0.051	+5.447	.009	.005	3	2
UCEC	RNA5SP412 →	+0.395	+1.493	<.001	.009	3	2
LUAD	MT4 →	+0.126	+5.584	<.001	.002	3	2
LUAD	RNU6-425P →	+0.569	+4.984	<.001	.005	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,714 associations by consensus.

SELENOTP2 by EPM2AIP1 expression — LUSC

Explore this box plot interactively →