EPHX4

Across TCGA patient cohorts, EPHX4 protein abundance is significantly associated with the RNA expression of many other genes, with 2,692 significant associations in total. GBM shows the largest number of these associations.

The most reproducible EPHX4-associated genes across cancer lineages are BCL10, FAM83B, and GRM5. Each is linked with EPHX4 in more than 1 cancer types. Because this analysis shows association rather than direction, both EPHX4-to-partner and partner-to-EPHX4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, EPHX4 versus BCL10 in LUAD, with a Pearson correlation of 0.46.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (EPHX4→partner) and Y-score (partner→EPHX4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	BCL10 →	+0.534	+0.943	.003	.007	3	2
LUAD	FAM83B →	+1.208	+0.771	.001	.004	3	2
GBM	GRM5 →	+1.088	+0.433	<.001	<.001	3	2
GBM	ERC2 →	+0.923	+0.374	<.001	<.001	3	2
GBM	BCYRN1 →	+1.226	+0.346	<.001	<.001	3	2
GBM	ERC2-IT1 →	+0.416	+0.347	.003	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,692 associations by consensus.

EPHX4 vs BCL10 — LUAD

Explore this scatter interactively →