EPHX4

Across TCGA patient cohorts, EPHX4 mutation is significantly associated with the RNA expression of many other genes, with 1,923 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible EPHX4-associated genes across cancer lineages are RNA5SP198, MIR615, and RNU6-1207P. Each is linked with EPHX4 in more than 2 cancer types. Because this analysis shows association rather than direction, both EPHX4-to-partner and partner-to-EPHX4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA5SP198 grouped by EPHX4-low versus EPHX4-high in CESC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (EPHX4→partner) and Y-score (partner→EPHX4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CESC	RNA5SP198 →	+0.224	+4.559	<.001	.006	3	3
CESC	MIR615 →	+0.608	+4.413	.001	.002	3	2
COAD	RNU6-1207P →	+0.618	+4.037	<.001	.004	3	2
COAD	RN7SL25P →	+0.517	+4.484	<.001	.002	3	2
UCEC	MIR7976 →	+0.255	+1.939	.005	.004	3	2
UCEC	LINC02438 →	+0.564	+2.137	<.001	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,923 associations by consensus.

RNA5SP198 by EPHX4 expression — CESC

Explore this box plot interactively →