EPHX4

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, EPHX4 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,811 significant associations in total. STOMACH shows the largest number of these associations.

The most reproducible EPHX4-associated GO terms across cancer lineages are Distal tubule morphogenesis, Nucleus organization, and Nuclear envelope organization. Each is linked with EPHX4 in more than 6 cancer types. Because this analysis shows association rather than direction, both EPHX4-to-partner and partner-to-EPHX4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Distal tubule morphogenesis grouped by EPHX4-low versus EPHX4-high in SOFT_TISSUE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (EPHX4→partner) and Y-score (partner→EPHX4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
SOFT_TISSUEDistal tubule morphogenesis →-0.307-1.035<.001<.00137
OESOPHAGUSNucleus organization →+0.065+1.211.002.00237
OESOPHAGUSNuclear envelope organization →+0.093+1.625.001.00137
SOFT_TISSUEAldosterone biosynthetic process →-0.782-0.754.002.00237
BREASTPositive regulation of chromosome organization →+0.066+1.272.003<.00137
OVARYGerm cell development →-0.026-1.051<.001.00637
Each partner links to its Q-omics profile. Showing the 6 strongest of 2,811 associations by consensus.

Distal tubule morphogenesis by EPHX4 expression — SOFT_TISSUE

Box plot of Distal tubule morphogenesis in EPHX4-low vs EPHX4-high samples in SOFT_TISSUE.

Explore this box plot interactively →

Exploration