EPHX3

Across TCGA patient cohorts, EPHX3 protein abundance is significantly associated with the RNA expression of many other genes, with 11,974 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible EPHX3-associated genes across cancer lineages are IRF1-AS1, TRBV26, and PTPRG. Each is linked with EPHX3 in more than 1 cancer types. Because this analysis shows association rather than direction, both EPHX3-to-partner and partner-to-EPHX3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, EPHX3 versus IRF1-AS1 in HNSC, with a Pearson correlation of -0.41.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (EPHX3→partner) and Y-score (partner→EPHX3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	IRF1-AS1 →	-0.841	-0.965	<.001	.003	3	2
HNSC	TRBV26 →	-0.531	-0.716	<.001	.009	3	2
LSCC	PTPRG →	-0.740	-1.001	.003	.009	3	2
HNSC	BICD1 →	-0.819	-0.776	.002	.004	3	2
LSCC	TTC14 →	-1.074	-1.307	.003	.005	3	2
HNSC	RNU6-674P →	-1.466	-1.320	.003	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,974 associations by consensus.

EPHX3 vs IRF1-AS1 — HNSC

Explore this scatter interactively →