EPHX3

Across TCGA cell cohorts, EPHX3 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,155 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible EPHX3-associated GO terms across cancer lineages are Viral transcription, Regulation of RNA splicing, and Regulation of mRNA processing. Each is linked with EPHX3 in more than 7 cancer types. Because this analysis shows association rather than direction, both EPHX3-to-partner and partner-to-EPHX3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Viral transcription grouped by EPHX3-low versus EPHX3-high in BLOOD_Lymphoma.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (EPHX3→partner) and Y-score (partner→EPHX3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	Viral transcription →	+0.059	+0.064	.004	.007	3	8
BLOOD_Leukemia	Regulation of RNA splicing →	+0.058	+0.068	<.001	<.001	3	7
SOFT_TISSUE	Regulation of mRNA processing →	+0.083	+0.125	<.001	.001	3	7
SOFT_TISSUE	Negative regulation of DNA-templated transcription, elongation →	+0.080	+0.100	<.001	.004	3	6
BLOOD_Leukemia	Regulation of DNA-templated DNA replication →	+0.064	+0.081	<.001	<.001	3	6
BONE	Establishment of spindle localization →	+0.113	+0.161	.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,155 associations by consensus.

Viral transcription by EPHX3 expression — BLOOD_Lymphoma

Explore this box plot interactively →