EPHB1

Across TCGA patient cohorts, EPHB1 protein abundance is significantly associated with the RNA expression of many other genes, with 3,090 significant associations in total. GBM shows the largest number of these associations.

The most reproducible EPHB1-associated genes across cancer lineages are KCNH1, RBPMS2P1, and RHEBP3. Each is linked with EPHB1 in more than 1 cancer types. Because this analysis shows association rather than direction, both EPHB1-to-partner and partner-to-EPHB1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, EPHB1 versus KCNH1 in GBM, with a Pearson correlation of 0.35.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (EPHB1→partner) and Y-score (partner→EPHB1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	KCNH1 →	+0.756	+0.508	.001	.001	3	2
GBM	RBPMS2P1 →	+0.924	+0.612	<.001	<.001	3	2
GBM	RHEBP3 →	+0.886	+0.607	<.001	<.001	3	2
GBM	RN7SKP244 →	+0.486	+0.402	<.001	<.001	3	2
OV	WWC1 →	-1.724	-2.620	.001	.005	3	1
OV	B4GALT2 →	+1.019	+2.620	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,090 associations by consensus.

EPHB1 vs KCNH1 — GBM

Explore this scatter interactively →