EPHA5

Across TCGA patient cohorts, EPHA5 RNA expression is significantly associated with the go_rna of many other GO terms, with 7,116 significant associations in total. STAD shows the largest number of these associations.

The most reproducible EPHA5-associated GO terms across cancer lineages are Golgi organization, Regulation of microtubule cytoskeleton organization, and Golgi vesicle transport. Each is linked with EPHA5 in more than 19 cancer types. Because this analysis shows association rather than direction, both EPHA5-to-partner and partner-to-EPHA5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Golgi organization grouped by EPHA5-low versus EPHA5-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (EPHA5→partner) and Y-score (partner→EPHA5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Golgi organization →	+0.053	+0.068	<.001	<.001	3	20
STAD	Regulation of microtubule cytoskeleton organization →	+0.049	+0.078	<.001	<.001	3	20
STAD	Golgi vesicle transport →	+0.063	+0.086	<.001	<.001	3	19
TGCT	Smoothened signaling pathway →	+0.058	+0.296	<.001	<.001	3	19
TGCT	Platelet-derived growth factor receptor signaling pathway →	+0.076	+0.407	<.001	<.001	3	18
STAD	Endoplasmic reticulum to Golgi vesicle-mediated transport →	+0.055	+0.079	<.001	<.001	3	18

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,116 associations by consensus.

Golgi organization by EPHA5 expression — STAD

Explore this box plot interactively →