EPHA5-AS1

Across TCGA patient cohorts, EPHA5-AS1 RNA expression is significantly associated with the go_rna of many other GO terms, with 7,051 significant associations in total. STAD shows the largest number of these associations.

The most reproducible EPHA5-AS1-associated GO terms across cancer lineages are Negative regulation of neurotransmitter transport, Respiratory chain complex IV assembly, and Regulation of smoothened signaling pathway. Each is linked with EPHA5-AS1 in more than 10 cancer types. Because this analysis shows association rather than direction, both EPHA5-AS1-to-partner and partner-to-EPHA5-AS1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of neurotransmitter transport grouped by EPHA5-AS1-low versus EPHA5-AS1-high in TGCT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (EPHA5-AS1→partner) and Y-score (partner→EPHA5-AS1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
TGCT	Negative regulation of neurotransmitter transport →	+0.042	+0.163	<.001	<.001	3	11
STAD	Respiratory chain complex IV assembly →	+0.045	+0.048	<.001	<.001	3	10
STAD	Regulation of smoothened signaling pathway →	+0.043	+0.051	<.001	<.001	3	10
STAD	Establishment of protein localization to membrane →	+0.054	+0.059	<.001	<.001	3	10
STAD	Microtubule polymerization →	+0.044	+0.063	<.001	<.001	3	10
TGCT	Non-canonical Wnt signaling pathway →	+0.054	+0.257	<.001	.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,051 associations by consensus.

Negative regulation of neurotransmitter transport by EPHA5-AS1 expression — TGCT

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