EPHA2

Across TCGA patient cohorts, EPHA2 RNA expression is significantly associated with the protein abundance of many other proteins, with 13,788 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible EPHA2-associated proteins across cancer lineages are ZNF185_S153, FGD4_S702, and ARAP3. Each is linked with EPHA2 in more than 4 cancer types. Because this analysis shows association rather than direction, both EPHA2-to-partner and partner-to-EPHA2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, EPHA2 versus ZNF185_S153 in HNSC, with a Pearson correlation of 0.43.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (EPHA2→partner) and Y-score (partner→EPHA2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	ZNF185_S153 →	+1.002	+1.104	<.001	<.001	3	5
UCEC	FGD4_S702 →	+0.623	+0.904	.004	.004	3	5
GBM	ARAP3 →	+0.544	+1.029	<.001	<.001	3	5
BRCA	RND3 →	+0.403	+0.885	.001	<.001	3	5
BRCA	SERPINB5 →	+1.438	+0.892	<.001	<.001	3	5
LSCC	ITGB4_T1530 →	+1.252	+1.269	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,788 associations by consensus.

EPHA2 vs ZNF185_S153 — HNSC

Explore this scatter interactively →