EPGN

Across TCGA patient cohorts, EPGN RNA expression is significantly associated with the RNA expression of many other genes, with 13,155 significant associations in total. KIRP shows the largest number of these associations.

The most reproducible EPGN-associated genes across cancer lineages are BICD2, ZNF770, and EREG. Each is linked with EPGN in more than 19 cancer types. Because this analysis shows association rather than direction, both EPGN-to-partner and partner-to-EPGN results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, EPGN versus BICD2 in ESCA, with a Pearson correlation of 0.44.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (EPGN→partner) and Y-score (partner→EPGN) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ESCA	BICD2 →	+1.453	+1.881	<.001	<.001	3	20
THYM	ZNF770 →	+1.411	+0.529	<.001	.001	3	19
LAML	EREG →	+2.625	+1.722	<.001	<.001	3	19
ESCA	RNF217 →	+1.458	+1.270	<.001	<.001	3	19
ESCA	DENND2C →	+2.097	+2.101	<.001	<.001	3	18
THCA	NABP1 →	+0.717	+0.138	<.001	<.001	3	17

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,155 associations by consensus.

EPGN vs BICD2 — ESCA

Explore this scatter interactively →