EPGN

RNA expression — cross-omics
Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, EPGN RNA expression is significantly associated with the protein abundance of many other proteins, with 15,592 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible EPGN-associated proteins across cancer lineages are AHNAK2_S5707, ZYX, and TNKS1BP1_S1138. Each is linked with EPGN in more than 5 cancer types. Because this analysis shows association rather than direction, both EPGN-to-partner and partner-to-EPGN results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, EPGN versus AHNAK2_S5707 in LUAD, with a Pearson correlation of 0.46.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (EPGN→partner) and Y-score (partner→EPGN) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LUADAHNAK2_S5707 →+1.958+1.110<.001.00136
BRCAZYX →+0.330+0.447<.001<.00135
LUADTNKS1BP1_S1138 →+0.882+1.058<.001<.00135
HNSCSERPINB8 →+0.467+1.486<.001<.00134
HNSCSH3BGRL3 →+0.441+2.312<.001<.00134
OVSNRPD2 →-0.208-0.691.002.00234
Each partner links to its Q-omics profile. Showing the 6 strongest of 15,592 associations by consensus.

EPGN vs AHNAK2_S5707 — LUAD

Per-sample scatter of EPGN vs AHNAK2_S5707 in LUAD (Pearson r = 0.46).

Explore this scatter interactively →

Exploration