EPGN

Across TCGA cell cohorts, EPGN RNA expression is significantly associated with the go_rna of many other GO terms, with 1,393 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible EPGN-associated GO terms across cancer lineages are Hemidesmosome assembly, Cell-substrate junction assembly, and Membrane assembly. Each is linked with EPGN in more than 6 cancer types. Because this analysis shows association rather than direction, both EPGN-to-partner and partner-to-EPGN results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Hemidesmosome assembly grouped by EPGN-low versus EPGN-high in BREAST.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (EPGN→partner) and Y-score (partner→EPGN) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	Hemidesmosome assembly →	+0.300	+1.622	<.001	.001	3	7
PANCREAS	Cell-substrate junction assembly →	+0.210	+1.767	<.001	<.001	3	6
BREAST	Membrane assembly →	+0.067	+1.172	<.001	.002	3	6
BREAST	Macrophage apoptotic process →	+0.148	+1.072	.003	.004	3	6
PANCREAS	Cell-substrate junction organization →	+0.192	+1.632	<.001	.002	3	6
OESOPHAGUS	Regulation of ubiquitin-dependent protein catabolic process →	+0.059	+1.318	.006	.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,393 associations by consensus.

Hemidesmosome assembly by EPGN expression — BREAST

Explore this box plot interactively →