EPDR1

Across TCGA pan-cancer cohorts, EPDR1 mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated EPDR1 data layer compared with 25 for mass-spec protein and 4 for mutation status.

The strongest signal is observed in clear cell renal cell carcinoma (CCRCC), where higher EPDR1 mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated EPDR1 expression acts as an unfavorable survival marker, although some lineages such as PDAC show a favorable association.

CCRCC, LSCC, and UCEC are the cancer types where EPDR1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
CCRCC	DFS	Median	All	0.851	0.980	.001	86	view →
LSCC	DFS	Tertile	II,III,IV	0.526	0.916	.001	21	view →
UCEC	OS	Median	II,III,IV	0.620	1.000	.011	20	view →
PDAC	OS	Tertile	All	0.945	0.794	.013	13	view →
HNSC	DFS	Median	II,III,IV	0.908	0.980	.031	3	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

EPDR1–CCRCC (DFS)

Open the CCRCC breakdown →