EPDR1

Across TCGA pan-cancer cohorts, EPDR1 RNA differs between tumor and matched normal tissue in 12 of 18 cancer types tested, making tumor–normal expression one of EPDR1’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal papillary cell carcinoma (KIRP), where EPDR1 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types EPDR1 is over-expressed in tumor, although a few such as LUSC and UCEC show the opposite, repressed pattern.

KIRP, KIRC, and LIHC are the cancer types where EPDR1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in EPDR1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRP	Male	II,III,IV	+1.541	<.001	11	view →
KIRC	All	IV	+0.801	<.001	11	view →
LIHC	Male	II,III,IV	+1.482	<.001	9	view →
LUSC	All	III,IV	−2.705	<.001	8	view →
KICH	Male	All	+1.327	<.001	7	view →
UCEC	All	All	−1.861	<.001	6	view →
BRCA	All	All	−1.378	<.001	6	view →
CHOL	All	All	+1.617	<.001	5	view →
COAD	All	All	+0.741	.002	5	view →
BLCA	Male	III,IV	−1.880	<.001	4	view →
LUAD	All	All	−0.487	.004	3	view →
THCA	All	II,III,IV	−0.432	.038	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 12 lineages.

EPDR1–KIRP

Open the KIRP breakdown →