EPDR1

Across TCGA cell cohorts, EPDR1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,305 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible EPDR1-associated GO terms across cancer lineages are Modulation of excitatory postsynaptic potential, T-helper 17 cell differentiation, and Symbiont entry into host. Each is linked with EPDR1 in more than 9 cancer types. Because this analysis shows association rather than direction, both EPDR1-to-partner and partner-to-EPDR1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Modulation of excitatory postsynaptic potential grouped by EPDR1-low versus EPDR1-high in LUNG_NSCLC_LUAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (EPDR1→partner) and Y-score (partner→EPDR1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	Modulation of excitatory postsynaptic potential →	-0.079	-1.759	<.001	.001	3	10
SOFT_TISSUE	T-helper 17 cell differentiation →	+0.098	+1.842	.006	.009	3	9
OVARY	Symbiont entry into host →	+0.097	+2.079	.001	.002	3	9
OVARY	Symbiont entry into host cell →	+0.097	+2.079	.001	.002	3	9
BREAST	Glycolytic process through fructose-6-phosphate →	+0.110	+2.080	<.001	.002	3	9
BREAST	Glycolytic process through glucose-6-phosphate →	+0.110	+2.080	<.001	.002	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,305 associations by consensus.

Modulation of excitatory postsynaptic potential by EPDR1 expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →