EPC2

Across TCGA patient cohorts, EPC2 protein abundance is significantly associated with the RNA expression of many other genes, with 7,938 significant associations in total. GBM shows the largest number of these associations.

The most reproducible EPC2-associated genes across cancer lineages are ACVR2A, RPIA, and WDCP. Each is linked with EPC2 in more than 3 cancer types. Because this analysis shows association rather than direction, both EPC2-to-partner and partner-to-EPC2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, EPC2 versus ACVR2A in HNSC, with a Pearson correlation of 0.36.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (EPC2→partner) and Y-score (partner→EPC2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	ACVR2A →	+0.533	+0.225	<.001	.001	3	4
HNSC	RPIA →	+0.658	+0.319	<.001	<.001	3	4
LSCC	WDCP →	+0.593	+0.218	<.001	<.001	3	4
HNSC	C2orf68 →	+0.586	+0.382	<.001	.001	3	4
HNSC	KLHL23 →	+1.179	+0.313	.002	.004	3	4
HNSC	NIFK-AS1 →	+0.546	+0.375	.002	.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,938 associations by consensus.

EPC2 vs ACVR2A — HNSC

Explore this scatter interactively →