EPC2

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, EPC2 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,266 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible EPC2-associated GO terms across cancer lineages are Positive regulation of organelle assembly, Positive regulation of double-strand break repair, and Positive regulation of mRNA catabolic process. Each is linked with EPC2 in more than 16 cancer types. Because this analysis shows association rather than direction, both EPC2-to-partner and partner-to-EPC2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of organelle assembly grouped by EPC2-low versus EPC2-high in OVARY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (EPC2→partner) and Y-score (partner→EPC2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
OVARYPositive regulation of organelle assembly →+0.063+0.673<.001<.001317
STOMACHPositive regulation of double-strand break repair →+0.081+0.732.001.005317
BLOOD_LymphomaPositive regulation of mRNA catabolic process →+0.061+0.823.001.004317
LUNG_SCLCRegulation of double-strand break repair via homologous recombination →+0.090+0.812<.001.001316
LUNG_SCLCPositive regulation of mRNA metabolic process →+0.066+0.718<.001<.001316
STOMACHPositive regulation of double-strand break repair via homologous recombination →+0.097+0.939<.001<.001316
Each partner links to its Q-omics profile. Showing the 6 strongest of 4,266 associations by consensus.

Positive regulation of organelle assembly by EPC2 expression — OVARY

Box plot of Positive regulation of organelle assembly in EPC2-low vs EPC2-high samples in OVARY.

Explore this box plot interactively →

Exploration