EPB41L5

Across TCGA patient cohorts, EPB41L5 mutation is significantly associated with the RNA expression of many other genes, with 3,329 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible EPB41L5-associated genes across cancer lineages are SLC6A17-AS1, RNU6-4P, and MIR6134. Each is linked with EPB41L5 in more than 2 cancer types. Because this analysis shows association rather than direction, both EPB41L5-to-partner and partner-to-EPB41L5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SLC6A17-AS1 grouped by EPB41L5-low versus EPB41L5-high in BRCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (EPB41L5→partner) and Y-score (partner→EPB41L5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	SLC6A17-AS1 →	+0.101	+4.080	<.001	.004	3	3
UCEC	RNU6-4P →	+0.343	+1.756	.002	<.001	3	3
BRCA	MIR6134 →	+0.121	+7.057	<.001	.009	3	2
UCEC	PHF5A →	+0.437	+2.536	<.001	<.001	3	2
LUAD	KCNH1-IT1 →	+0.784	+3.293	<.001	.008	3	2
BRCA	MIR23C →	+0.757	+4.401	<.001	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,329 associations by consensus.

SLC6A17-AS1 by EPB41L5 expression — BRCA

Explore this box plot interactively →