EPB41L3

Across TCGA cell cohorts, EPB41L3 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,952 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible EPB41L3-associated GO terms across cancer lineages are Protein localization to axon, Protein localization to juxtaparanode region of axon, and Retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum. Each is linked with EPB41L3 in more than 6 cancer types. Because this analysis shows association rather than direction, both EPB41L3-to-partner and partner-to-EPB41L3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Protein localization to axon grouped by EPB41L3-low versus EPB41L3-high in BLOOD_Leukemia.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (EPB41L3→partner) and Y-score (partner→EPB41L3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	Protein localization to axon →	+1.225	+2.598	<.001	<.001	3	7
BONE	Protein localization to juxtaparanode region of axon →	+1.186	+2.338	<.001	.008	3	7
LUNG_NSCLC_LUAD	Retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum →	+0.080	+2.671	<.001	<.001	3	7
LIVER	Cytoplasmic translational initiation →	+0.072	+2.508	.003	.005	3	6
BLOOD_Leukemia	Protein localization to paranode region of axon →	+1.133	+2.846	<.001	<.001	3	6
LARGE_INTESTINE	Purine ribonucleoside triphosphate metabolic process →	+0.045	+1.158	.001	.007	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,952 associations by consensus.

Protein localization to axon by EPB41L3 expression — BLOOD_Leukemia

Explore this box plot interactively →