EPB41L3

Across TCGA cell cohorts, EPB41L3 mutation is significantly associated with the RNA expression of many other genes, with 212 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible EPB41L3-associated genes across cancer lineages are OR10K1, FABP12, and ELAC2. Each is linked with EPB41L3 in more than 1 cancer types. Because this analysis shows association rather than direction, both EPB41L3-to-partner and partner-to-EPB41L3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR10K1 grouped by EPB41L3-low versus EPB41L3-high in BLOOD_Lymphoma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (EPB41L3→partner) and Y-score (partner→EPB41L3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	OR10K1 →	+0.005	+2.867	<.001	.009	3	2
LUNG_SCLC	FABP12 →	+0.253	+4.106	<.001	<.001	3	2
SKIN	ELAC2 →	+0.564	+3.064	.004	.009	3	2
LUNG_NSCLC_LUAD	GJA8 →	+0.299	+2.564	.006	.007	3	2
LARGE_INTESTINE	MAGEB4 →	+0.008	+2.830	.001	.004	3	2
LARGE_INTESTINE	DERL2 →	+0.424	+3.502	.008	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 212 associations by consensus.

OR10K1 by EPB41L3 expression — BLOOD_Lymphoma

Explore this box plot interactively →