EPB41L2

Across TCGA patient cohorts, EPB41L2 protein abundance is significantly associated with the RNA expression of many other genes, with 16,131 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible EPB41L2-associated genes across cancer lineages are ABCA8, CPED1, and ENPP2. Each is linked with EPB41L2 in more than 8 cancer types. Because this analysis shows association rather than direction, both EPB41L2-to-partner and partner-to-EPB41L2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, EPB41L2 versus ABCA8 in GBM, with a Pearson correlation of 0.37.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (EPB41L2→partner) and Y-score (partner→EPB41L2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	ABCA8 →	+1.138	+0.450	.001	<.001	3	9
UCEC	CPED1 →	+0.872	+0.515	.003	.002	3	8
GBM	ENPP2 →	+1.122	+0.295	<.001	<.001	3	8
BRCA	ABCA9 →	+0.876	+0.352	<.001	<.001	3	8
HNSC	SYNPO2 →	+1.524	+0.461	<.001	<.001	3	8
OV	PGR →	+1.925	+0.577	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,131 associations by consensus.

EPB41L2 vs ABCA8 — GBM

Explore this scatter interactively →