EP300

Across TCGA patient cohorts, EP300 RNA expression is significantly associated with the protein abundance of many other proteins, with 11,120 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible EP300-associated proteins across cancer lineages are ST13, PBRM1, and SF3B3. Each is linked with EP300 in more than 4 cancer types. Because this analysis shows association rather than direction, both EP300-to-partner and partner-to-EP300 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, EP300 versus ST13 in LSCC, with a Pearson correlation of 0.45.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (EP300→partner) and Y-score (partner→EP300) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	ST13 →	+0.395	+0.573	<.001	<.001	3	5
GBM	PBRM1 →	+0.337	+0.406	<.001	.004	3	4
GBM	SF3B3 →	+0.234	+0.383	.002	.002	3	4
GBM	XRCC6 →	+0.261	+0.420	<.001	<.001	3	4
LSCC	HDHD5 →	+0.451	+0.366	<.001	.002	3	4
LSCC	DHX9 →	+0.217	+0.490	.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,120 associations by consensus.

EP300 vs ST13 — LSCC

Explore this scatter interactively →