ENTR1

Across TCGA patient cohorts, ENTR1 mutation is significantly associated with the RNA expression of many other genes, with 1,357 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ENTR1-associated genes across cancer lineages are MTCYBP8, VTRNA2-2P, and MIR920. Each is linked with ENTR1 in more than 1 cancer types. Because this analysis shows association rather than direction, both ENTR1-to-partner and partner-to-ENTR1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MTCYBP8 grouped by ENTR1-low versus ENTR1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ENTR1→partner) and Y-score (partner→ENTR1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	MTCYBP8 →	+0.042	+2.920	<.001	.008	3	2
COAD	VTRNA2-2P →	+0.434	+5.412	<.001	.001	3	2
CESC	MIR920 →	+0.371	+4.539	<.001	.008	3	1
CESC	MTATP6P13 →	+0.053	+4.969	<.001	.004	3	1
UCEC	COX5A →	+0.455	+4.180	.001	<.001	3	1
UCEC	SELENOW →	+0.443	+2.732	.006	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,357 associations by consensus.

MTCYBP8 by ENTR1 expression — UCEC

Explore this box plot interactively →