ENTR1

Across TCGA patient cohorts, ENTR1 mutation is significantly associated with the immune_cell of many other genes, with 7 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ENTR1-associated genes across cancer lineages are Eosinophils, MPP, and GMP. Each is linked with ENTR1 in more than 1 cancer types. Because this analysis shows association rather than direction, both ENTR1-to-partner and partner-to-ENTR1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Eosinophils grouped by ENTR1-low versus ENTR1-high in STAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ENTR1→partner) and Y-score (partner→ENTR1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Eosinophils →	+0.029	+3.201	.044	.030	3	2
COAD	MPP →	+0.026	+2.233	.001	.045	3	2
HNSC	GMP →	+0.112	+4.069	<.001	.031	3	2
HNSC	Platelets →	+0.069	+4.100	<.001	.029	3	1
UCEC	CD8+ naive T-cells →	+0.031	+2.457	.003	.001	3	1
UCEC	lymphatic Endothelial cells →	-0.021	-1.853	.027	.017	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 7 associations by consensus.

Eosinophils by ENTR1 expression — STAD

Explore this box plot interactively →