ENTR1

Across TCGA cell cohorts, ENTR1 mutation is significantly associated with the RNA expression of many other genes, with 22 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ENTR1-associated genes across cancer lineages are GPR42, BSND, and OR1D5. Each is linked with ENTR1 in more than 1 cancer types. Because this analysis shows association rather than direction, both ENTR1-to-partner and partner-to-ENTR1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, GPR42 grouped by ENTR1-low versus ENTR1-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ENTR1→partner) and Y-score (partner→ENTR1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	GPR42 →	+0.044	+4.152	<.001	.009	3	1
BLOOD_Leukemia	BSND →	+0.010	+4.551	.003	.004	3	1
BLOOD_Leukemia	OR1D5 →	+0.024	+4.969	<.001	.003	3	1
BREAST	REG1B →	+1.039	+5.169	<.001	.005	3	1
BREAST	OR10AG1 →	+0.013	+5.169	<.001	.005	3	1
LARGE_INTESTINE	CHST8 →	+0.125	+3.643	.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 22 associations by consensus.

GPR42 by ENTR1 expression — BLOOD_Leukemia

Explore this box plot interactively →