ENTPD3

Across TCGA cell cohorts, ENTPD3 mutation is significantly associated with the RNA expression of many other genes, with 4 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ENTPD3-associated genes across cancer lineages are IFNG, C8A, and OR52A1. Each is linked with ENTPD3 in more than 1 cancer types. Because this analysis shows association rather than direction, both ENTPD3-to-partner and partner-to-ENTPD3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, IFNG grouped by ENTPD3-low versus ENTPD3-high in CNS.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ENTPD3→partner) and Y-score (partner→ENTPD3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CNS	IFNG →	+0.078	+5.321	<.001	.005	3	1
LARGE_INTESTINE	C8A →	+0.026	+3.684	<.001	.006	3	1
LARGE_INTESTINE	OR52A1 →	+0.010	+4.347	<.001	.001	3	1
LARGE_INTESTINE	LCE5A →	+0.187	+4.688	.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

IFNG by ENTPD3 expression — CNS

Explore this box plot interactively →