ENTPD2

Across TCGA patient cohorts, ENTPD2 mutation is significantly associated with the RNA expression of many other genes, with 80 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ENTPD2-associated genes across cancer lineages are MIR4694, MIR4736, and CDRT8. Each is linked with ENTPD2 in more than 1 cancer types. Because this analysis shows association rather than direction, both ENTPD2-to-partner and partner-to-ENTPD2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR4694 grouped by ENTPD2-low versus ENTPD2-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ENTPD2→partner) and Y-score (partner→ENTPD2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	MIR4694 →	+0.349	+3.766	<.001	.001	3	1
SKCM	MIR4736 →	+0.330	+4.634	<.001	.003	3	1
SKCM	CDRT8 →	+0.142	+3.448	.001	.001	3	1
UCEC	MIR6803 →	+0.396	+6.156	<.001	<.001	3	1
UCEC	PRAMEF13 →	+0.038	+4.132	<.001	.009	3	1
BRCA	RNU6-324P →	+0.386	+7.342	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 80 associations by consensus.

MIR4694 by ENTPD2 expression — SKCM

Explore this box plot interactively →