ENSA

Across TCGA patient cohorts, ENSA RNA expression is significantly associated with the protein abundance of many other proteins, with 16,878 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible ENSA-associated proteins across cancer lineages are RPRD2, POGZ, and BROX. Each is linked with ENSA in more than 7 cancer types. Because this analysis shows association rather than direction, both ENSA-to-partner and partner-to-ENSA results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ENSA versus RPRD2 in HNSC, with a Pearson correlation of 0.38.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ENSA→partner) and Y-score (partner→ENSA) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	RPRD2 →	+0.395	+0.490	<.001	<.001	3	8
GBM	POGZ →	+0.258	+0.284	.006	<.001	3	7
UCEC	BROX →	+0.533	+0.513	<.001	<.001	3	7
BRCA	OTUD7B →	+0.265	+0.430	<.001	<.001	3	7
LSCC	GATAD2B →	+0.474	+0.722	<.001	<.001	3	7
UCEC	TIPRL →	+0.252	+0.509	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,878 associations by consensus.

ENSA vs RPRD2 — HNSC

Explore this scatter interactively →