ENPP6

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, ENPP6 protein abundance is significantly associated with the RNA expression of many other genes, with 4,040 significant associations in total. GBM shows the largest number of these associations.

The most reproducible ENPP6-associated genes across cancer lineages are ABCG2, PEG3, and RN7SL471P. Each is linked with ENPP6 in more than 2 cancer types. Because this analysis shows association rather than direction, both ENPP6-to-partner and partner-to-ENPP6 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ENPP6 versus ABCG2 in OV, with a Pearson correlation of 0.54.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ENPP6→partner) and Y-score (partner→ENPP6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
OVABCG2 →+0.962+1.784<.001<.00133
OVPEG3 →+1.244+1.561.001<.00133
HNSCRN7SL471P →+3.881+0.300<.001.00733
GBMMCF2 →+0.509+0.714.005.00232
OVADAP1 →+0.821+1.318<.001.00332
OVEFCC1 →+0.804+1.136<.001<.00132
Each partner links to its Q-omics profile. Showing the 6 strongest of 4,040 associations by consensus.

ENPP6 vs ABCG2 — OV

Per-sample scatter of ENPP6 vs ABCG2 in OV (Pearson r = 0.54).

Explore this scatter interactively →

Exploration