ENPP6

Across TCGA cell cohorts, ENPP6 RNA expression is significantly associated with the go_rna of many other GO terms, with 974 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible ENPP6-associated GO terms across cancer lineages are Sodium ion transmembrane transport, Positive regulation of protein deubiquitination, and Cellular response to nutrient levels. Each is linked with ENPP6 in more than 4 cancer types. Because this analysis shows association rather than direction, both ENPP6-to-partner and partner-to-ENPP6 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Sodium ion transmembrane transport grouped by ENPP6-low versus ENPP6-high in BLOOD_Leukemia.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ENPP6→partner) and Y-score (partner→ENPP6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	Sodium ion transmembrane transport →	-0.019	-0.210	.005	.005	3	5
BREAST	Positive regulation of protein deubiquitination →	+0.109	+0.268	<.001	.008	3	4
BLOOD_Lymphoma	Cellular response to nutrient levels →	+0.037	+0.368	<.001	.006	3	4
BLOOD_Lymphoma	Positive regulation of interferon-beta production →	+0.045	+0.200	.001	.009	3	4
SKIN	Positive regulation of mRNA metabolic process →	+0.036	+0.086	<.001	.009	3	4
BLOOD_Leukemia	Positive regulation of type I interferon production →	+0.021	+0.153	.006	.005	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 974 associations by consensus.

Sodium ion transmembrane transport by ENPP6 expression — BLOOD_Leukemia

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