ENPP4

Across TCGA patient cohorts, ENPP4 RNA expression is significantly associated with the protein abundance of many other proteins, with 20,020 significant associations in total. GBM shows the largest number of these associations.

The most reproducible ENPP4-associated proteins across cancer lineages are CD2AP, TMEM63A, and DDAH1. Each is linked with ENPP4 in more than 6 cancer types. Because this analysis shows association rather than direction, both ENPP4-to-partner and partner-to-ENPP4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ENPP4 versus CD2AP in GBM, with a Pearson correlation of 0.45.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ENPP4→partner) and Y-score (partner→ENPP4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	CD2AP →	+0.366	+0.978	<.001	<.001	3	7
UCEC	TMEM63A →	+0.632	+0.651	<.001	<.001	3	6
BRCA	DDAH1 →	+0.747	+1.310	<.001	<.001	3	6
CCRCC	EEF2 →	-0.230	-0.528	.001	<.001	3	6
GBM	UTRN →	+0.299	+0.983	.001	.004	3	5
GBM	PGM5 →	+0.673	+1.024	.001	.009	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 20,020 associations by consensus.

ENPP4 vs CD2AP — GBM

Explore this scatter interactively →