ENPP2

Across TCGA patient cohorts, ENPP2 RNA expression is significantly associated with the protein abundance of many other proteins, with 25,047 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible ENPP2-associated proteins across cancer lineages are TBC1D2B, PES1, and HAAO. Each is linked with ENPP2 in more than 8 cancer types. Because this analysis shows association rather than direction, both ENPP2-to-partner and partner-to-ENPP2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ENPP2 versus TBC1D2B in LSCC, with a Pearson correlation of 0.61.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ENPP2→partner) and Y-score (partner→ENPP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	TBC1D2B →	+0.345	+0.806	<.001	<.001	3	9
LSCC	PES1 →	-0.394	-0.670	<.001	<.001	3	9
OV	HAAO →	+0.461	+0.790	<.001	<.001	3	9
LSCC	STAB1 →	+0.451	+0.929	<.001	<.001	3	8
BRCA	NID1 →	+0.555	+1.332	<.001	<.001	3	8
BRCA	OLFML1 →	+0.897	+1.291	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 25,047 associations by consensus.

ENPP2 vs TBC1D2B — LSCC

Explore this scatter interactively →