ENPEP

Across TCGA patient cohorts, ENPEP protein abundance is significantly associated with the RNA expression of many other genes, with 15,367 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible ENPEP-associated genes across cancer lineages are LAMA4, CCDC102B, and ADGRL4. Each is linked with ENPEP in more than 6 cancer types. Because this analysis shows association rather than direction, both ENPEP-to-partner and partner-to-ENPEP results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ENPEP versus LAMA4 in OV, with a Pearson correlation of 0.62.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ENPEP→partner) and Y-score (partner→ENPEP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	LAMA4 →	+1.127	+0.550	<.001	<.001	3	7
OV	CCDC102B →	+0.924	+0.712	<.001	<.001	3	7
OV	ADGRL4 →	+0.841	+0.485	<.001	<.001	3	7
OV	NNMT →	+1.964	+0.618	<.001	<.001	3	7
GBM	COL3A1 →	+2.037	+0.518	<.001	<.001	3	7
OV	TIE1 →	+0.789	+0.636	.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,367 associations by consensus.

ENPEP vs LAMA4 — OV

Explore this scatter interactively →