ENPEP

Across TCGA cell cohorts, ENPEP RNA expression is significantly associated with the go_rna of many other GO terms, with 1,804 significant associations in total. STOMACH shows the largest number of these associations.

The most reproducible ENPEP-associated GO terms across cancer lineages are Positive regulation of protein exit from endoplasmic reticulum, Regulation of intrinsic apoptotic signaling pathway, and Monoatomic anion transmembrane transport. Each is linked with ENPEP in more than 7 cancer types. Because this analysis shows association rather than direction, both ENPEP-to-partner and partner-to-ENPEP results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of protein exit from endoplasmic reticulum grouped by ENPEP-low versus ENPEP-high in LARGE_INTESTINE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ENPEP→partner) and Y-score (partner→ENPEP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	Positive regulation of protein exit from endoplasmic reticulum →	+0.075	+0.546	<.001	.001	3	8
STOMACH	Regulation of intrinsic apoptotic signaling pathway →	+0.082	+0.703	<.001	.001	3	7
OVARY	Monoatomic anion transmembrane transport →	-0.042	-0.585	.006	.003	3	7
SOFT_TISSUE	Cytoplasmic translation →	+0.057	+0.361	<.001	.008	3	7
SKIN	Regulation of syncytium formation by plasma membrane fusion →	+0.079	+0.447	<.001	.008	3	7
PANCREAS	Protein targeting →	+0.035	+0.391	<.001	.005	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,804 associations by consensus.

Positive regulation of protein exit from endoplasmic reticulum by ENPEP expression — LARGE_INTESTINE

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