ENOX2

Across TCGA cell cohorts, ENOX2 mutation is significantly associated with the RNA expression of many other genes, with 4 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ENOX2-associated genes across cancer lineages are OR4F21, FAM153B, and KLHL34. Each is linked with ENOX2 in more than 1 cancer types. Because this analysis shows association rather than direction, both ENOX2-to-partner and partner-to-ENOX2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR4F21 grouped by ENOX2-low versus ENOX2-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ENOX2→partner) and Y-score (partner→ENOX2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	OR4F21 →	+0.198	+3.878	<.001	.003	3	1
LARGE_INTESTINE	FAM153B →	+0.601	+3.748	<.001	.004	3	1
LARGE_INTESTINE	KLHL34 →	+0.084	+4.115	.009	.001	3	1
LARGE_INTESTINE	NEXMIF →	+0.261	+3.196	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

OR4F21 by ENOX2 expression — LARGE_INTESTINE

Explore this box plot interactively →