ENOX1-AS1

Across TCGA pan-cancer cohorts, ENOX1-AS1 RNA is linked to patient survival in 22 of 34 cancer types, making it the most broadly survival-associated ENOX1-AS1 data layer.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher ENOX1-AS1 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated ENOX1-AS1 expression acts as an unfavorable survival marker, although some lineages such as SKCM and ESCA show a favorable association.

KIRC, MESO, and UVM are the cancer types where ENOX1-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRC	OS	Median	All	0.526	0.716	<.001	142	view →
MESO	DFS	Median	All	0.239	0.441	<.001	114	view →
UVM	OS	Tertile	All	0.494	0.883	<.001	108	view →
ACC	OS	Tertile	All	0.285	0.681	.002	54	view →
OV	OS	Median	III,IV	0.787	0.870	.007	36	view →
SKCM	OS	Tertile	All	0.851	0.753	.013	18	view →
KICH	OS	Tertile	III,IV	0.178	0.847	<.001	18	view →
LUSC	OS	Quartile	II,III,IV	0.237	0.434	.010	18	view →
READ	OS	Tertile	IV	0.077	1.000	.014	13	view →
BRCA	DFS	Tertile	All	0.877	0.922	.005	12	view →
LUAD	DFS	Median	IV	0.298	0.658	.034	12	view →
ESCA	OS	Tertile	III,IV	0.583	0.329	.009	12	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 22 lineages.

ENOX1-AS1–KIRC (OS)

Open the KIRC breakdown →