ENOSF1

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, ENOSF1 mutation is significantly associated with the RNA expression of many other genes, with 3,381 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ENOSF1-associated genes across cancer lineages are NF1P10, RNA5SP422, and FRG2GP. Each is linked with ENOSF1 in more than 2 cancer types. Because this analysis shows association rather than direction, both ENOSF1-to-partner and partner-to-ENOSF1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, NF1P10 grouped by ENOSF1-low versus ENOSF1-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ENOSF1→partner) and Y-score (partner→ENOSF1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
SKCMNF1P10 →+0.981+4.875<.001.00233
UCECRNA5SP422 →+0.696+2.019<.001.00533
BLCAFRG2GP →+0.209+4.788<.001.00633
CESCLINC02559 →+1.780+6.342<.001.00132
CESCFAM8A2P →+0.056+5.539<.001.00432
CESCNAV2-IT1 →+0.306+5.306<.001.00632
Each partner links to its Q-omics profile. Showing the 6 strongest of 3,381 associations by consensus.

NF1P10 by ENOSF1 expression — SKCM

Box plot of NF1P10 in ENOSF1-low vs ENOSF1-high samples in SKCM.

Explore this box plot interactively →

Exploration