Across TCGA patient cohorts, ENO4 RNA expression is significantly associated with the protein abundance of many other proteins, with 17,445 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible ENO4-associated proteins across cancer lineages are LZTFL1, SHTN1, and SPA17. Each is linked with ENO4 in more than 5 cancer types. Because this analysis shows association rather than direction, both ENO4-to-partner and partner-to-ENO4 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ENO4→partner) and Y-score (partner→ENO4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	LZTFL1 →	+0.679	+0.459	<.001	<.001	3	6
GBM	SHTN1 →	+0.480	+0.486	<.001	<.001	3	5
GBM	SPA17 →	+1.086	+0.814	<.001	<.001	3	5
LSCC	ANP32A →	+0.349	+0.627	<.001	<.001	3	5
HNSC	UPP1 →	-0.639	-0.370	.003	.007	3	4
LSCC	MGA_S3059 →	+0.468	+0.568	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 17,445 associations by consensus.

Exploration

ENO4 survival (RNA) · tumor vs normal (RNA) · all ENO4 data types