ENO2

Across TCGA patient cohorts, ENO2 protein abundance is significantly associated with the RNA expression of many other genes, with 15,034 significant associations in total. GBM shows the largest number of these associations.

The most reproducible ENO2-associated genes across cancer lineages are TRPC1, EFEMP2, and GLRB. Each is linked with ENO2 in more than 6 cancer types. Because this analysis shows association rather than direction, both ENO2-to-partner and partner-to-ENO2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ENO2 versus TRPC1 in HNSC, with a Pearson correlation of 0.38.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ENO2→partner) and Y-score (partner→ENO2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	TRPC1 →	+0.999	+0.672	<.001	<.001	3	7
CCRCC	EFEMP2 →	+0.916	+0.606	<.001	<.001	3	6
HNSC	GLRB →	+0.766	+0.567	<.001	<.001	3	5
OV	P3H3 →	+0.969	+0.545	<.001	<.001	3	5
OV	PHC1 →	+0.935	+0.740	.001	.002	3	5
OV	LOXL3 →	+0.747	+0.960	.002	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,034 associations by consensus.

ENO2 vs TRPC1 — HNSC

Explore this scatter interactively →