ENO1

Across TCGA patient cohorts, ENO1 protein abundance is significantly associated with the RNA expression of many other genes, with 13,548 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible ENO1-associated genes across cancer lineages are PGK1, PYGL, and ANGPTL4. Each is linked with ENO1 in more than 7 cancer types. Because this analysis shows association rather than direction, both ENO1-to-partner and partner-to-ENO1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ENO1 versus PGK1 in UCEC, with a Pearson correlation of 0.37.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ENO1→partner) and Y-score (partner→ENO1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	PGK1 →	+1.108	+0.402	.001	<.001	3	8
OV	PYGL →	+0.934	+0.385	<.001	<.001	3	6
BRCA	ANGPTL4 →	+1.659	+0.545	<.001	<.001	3	6
HNSC	PLOD1 →	+0.791	+0.246	<.001	<.001	3	6
HNSC	ERRFI1 →	+0.940	+0.293	<.001	<.001	3	6
PDAC	EGLN3 →	+1.390	+0.382	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,548 associations by consensus.

ENO1 vs PGK1 — UCEC

Explore this scatter interactively →