ENO1

Across TCGA patient cohorts, ENO1 mutation is significantly associated with the RNA expression of many other genes, with 814 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ENO1-associated genes across cancer lineages are RNU6-147P, RN7SL498P, and RPL23AP82. Each is linked with ENO1 in more than 1 cancer types. Because this analysis shows association rather than direction, both ENO1-to-partner and partner-to-ENO1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-147P grouped by ENO1-low versus ENO1-high in CESC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ENO1→partner) and Y-score (partner→ENO1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CESC	RNU6-147P →	+0.443	+6.397	<.001	<.001	3	2
SKCM	RN7SL498P →	+0.098	+3.682	<.001	.004	3	2
UCEC	RPL23AP82 →	+0.411	+3.098	.001	<.001	3	2
UCEC	CENPP →	+0.244	+2.238	.008	.006	3	2
UCEC	IARS1 →	+0.645	+2.436	.001	.002	3	2
UCEC	FAM118B →	+0.518	+2.831	.002	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 814 associations by consensus.

RNU6-147P by ENO1 expression — CESC

Explore this box plot interactively →