ENO1

Across TCGA cell cohorts, ENO1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,933 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ENO1-associated GO terms across cancer lineages are Carbohydrate biosynthetic process, Establishment or maintenance of microtubule cytoskeleton polarity, and Mitotic spindle elongation. Each is linked with ENO1 in more than 15 cancer types. Because this analysis shows association rather than direction, both ENO1-to-partner and partner-to-ENO1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Carbohydrate biosynthetic process grouped by ENO1-low versus ENO1-high in KIDNEY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ENO1→partner) and Y-score (partner→ENO1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
KIDNEY	Carbohydrate biosynthetic process →	+0.122	+1.078	<.001	<.001	3	16
PANCREAS	Establishment or maintenance of microtubule cytoskeleton polarity →	+0.203	+1.183	<.001	<.001	3	15
PANCREAS	Mitotic spindle elongation →	+0.192	+0.880	<.001	<.001	3	15
PANCREAS	Mitotic spindle midzone assembly →	+0.192	+0.880	<.001	<.001	3	15
URINARY_TRACT	Positive regulation of mitotic cell cycle →	+0.093	+1.408	<.001	<.001	3	14
URINARY_TRACT	Regulation of meiotic cell cycle →	+0.101	+1.244	<.001	<.001	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,933 associations by consensus.

Carbohydrate biosynthetic process by ENO1 expression — KIDNEY

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