ENO1-IT1

Across TCGA pan-cancer cohorts, ENO1-IT1 RNA is linked to patient survival in 22 of 34 cancer types, making it the most broadly survival-associated ENO1-IT1 data layer.

The strongest signal is observed in thyroid carcinoma (THCA), where higher ENO1-IT1 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated ENO1-IT1 expression acts as an unfavorable survival marker, although some lineages such as READ and UCS show a favorable association.

THCA, UVM, and ACC are the cancer types where ENO1-IT1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
THCA	DFS	Quartile	All	0.709	0.935	<.001	101	view →
UVM	DFS	Quartile	III,IV	0.147	0.769	<.001	85	view →
ACC	DFS	Median	All	0.287	0.619	<.001	62	view →
LGG	DFS	Median	All	0.669	0.799	<.001	45	view →
KIRP	DFS	Median	III,IV	0.137	0.600	.001	45	view →
BRCA	DFS	Tertile	II,III,IV	0.921	0.970	<.001	42	view →
READ	DFS	Median	II,III,IV	0.929	0.682	.003	30	view →
KICH	OS	Median	III,IV	0.467	0.941	.006	27	view →
LUSC	DFS	Quartile	II,III,IV	0.500	0.903	<.001	27	view →
UCEC	OS	Tertile	II,III,IV	0.819	0.913	.010	24	view →
PAAD	DFS	Median	All	0.226	0.493	.002	20	view →
LUAD	DFS	Quartile	IV	0.389	0.898	.004	12	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 22 lineages.

ENO1-IT1–THCA (DFS)

Open the THCA breakdown →