ENO1-IT1

Across TCGA pan-cancer cohorts, ENO1-IT1 RNA differs between tumor and matched normal tissue in 12 of 18 cancer types tested, making tumor–normal expression one of ENO1-IT1’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where ENO1-IT1 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types ENO1-IT1 is over-expressed in tumor, although a few such as KICH and THCA show the opposite, repressed pattern.

KIRC, HNSC, and KICH are the cancer types where ENO1-IT1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in ENO1-IT1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRC	Male	IV	+0.540	<.001	11	view →
HNSC	All	All	+0.309	<.001	9	view →
KICH	Female	All	−0.475	<.001	8	view →
READ	Male	All	+0.423	.003	6	view →
UCEC	All	All	+0.389	.016	6	view →
BLCA	All	All	+0.552	.005	5	view →
COAD	All	All	+0.231	.002	5	view →
STAD	Male	All	+0.435	<.001	4	view →
THCA	All	All	−0.104	.016	3	view →
LUAD	Female	All	+0.506	.002	2	view →
CHOL	All	All	+0.467	.003	2	view →
LUSC	Male	All	+0.280	.020	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 12 lineages.

ENO1-IT1–KIRC

Open the KIRC breakdown →