ENO1-AS1

Across TCGA pan-cancer cohorts, ENO1-AS1 RNA is linked to patient survival in 23 of 34 cancer types, making it the most broadly survival-associated ENO1-AS1 data layer.

The strongest signal is observed in uterine carcinosarcoma (UCS), where higher ENO1-AS1 RNA is associated with better disease-free survival. In most high-consensus cancer types, elevated ENO1-AS1 expression acts as an unfavorable survival marker, although some lineages such as UCS and PAAD show a favorable association.

UCS, PAAD, and LUAD are the cancer types where ENO1-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCS	DFS	Median	II,III,IV	0.584	0.155	.001	66	view →
PAAD	DFS	Tertile	All	0.422	0.164	<.001	58	view →
LUAD	DFS	Tertile	III,IV	0.787	0.485	.002	45	view →
ACC	DFS	Median	All	0.201	0.714	.003	40	view →
KICH	OS	Quartile	All	0.807	1.000	.009	27	view →
OV	OS	Median	IV	0.744	0.498	.010	24	view →
BLCA	OS	Tertile	IV	0.206	0.673	.004	19	view →
MESO	OS	Tertile	All	0.519	0.325	.017	17	view →
COAD	DFS	Median	II,III,IV	0.353	0.683	.001	16	view →
HNSC	DFS	Median	II,III,IV	0.485	0.233	.009	9	view →
CHOL	DFS	Tertile	III,IV	0.492	0.094	.024	9	view →
SKCM	DFS	Quartile	All	0.790	0.651	.015	8	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 23 lineages.

ENO1-AS1–UCS (DFS)

Open the UCS breakdown →